AP 18

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TargetMol
Product Code: TAR-T21543
Supplier: TargetMol
CodeSizePrice
TAR-T21543-1mg1mg£95.00
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TAR-T21543-2mg2mg£106.00
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TAR-T21543-1mL1 mL * 10 mM (in DMSO)£128.00
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TAR-T21543-5mg5mg£128.00
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TAR-T21543-10mg10mg£161.00
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TAR-T21543-25mg25mg£262.00
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TAR-T21543-50mg50mg£374.00
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TAR-T21543-100mg100mg£546.00
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TAR-T21543-500mg500mg£1,091.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
AP 18 is a selective TRPA1 inhibitor.
CAS:
55224-94-7
Formula:
C11H12ClNO
Molecular Weight:
209.67
Pathway:
Membrane transporter/Ion channel
Purity:
0.98
SMILES:
CC(C(C)=CC1=CC=C(Cl)C=C1)=NO
Target:
TRP/TRPV Channel

References

1. Matt Petrus, et al. A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition. Mol Pain. 2007;3:40. Published 2007 Dec 17. 2. Jun Chen, et al. Pore dilation occurs in TRPA1 but not in TRPM8 channels. Mol Pain. 2009;5:3. Published 2009 Jan 21. 3. Thomas E Taylor-Clark, et al. Nitrooleic acid, an endogenous product of nitrative stress, activates nociceptive sensory nerves via the direct activation of TRPA1. Mol Pharmacol. 2009;75(4):820-829.