BU 224 hydrochloride

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TargetMol
Product Code: TAR-T22051
Supplier: TargetMol
CodeSizePrice
TAR-T22051-1mg1mg£98.00
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TAR-T22051-2mg2mg£109.00
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TAR-T22051-1mL1 mL * 10 mM (in DMSO)£134.00
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TAR-T22051-5mg5mg£135.00
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TAR-T22051-10mg10mg£168.00
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TAR-T22051-25mg25mg£282.00
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TAR-T22051-50mg50mg£409.00
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TAR-T22051-100mg100mg£561.00
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TAR-T22051-500mg500mg£1,107.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
BU 224 hydrochloride is a selective imidazoline I(2) binding site ligand and has antinociceptive and antidepressant-like activities.
CAS:
205437-64-5
Formula:
C12H12ClN3
Molecular Weight:
233.69
Pathway:
Neuroscience
Purity:
0.992
SMILES:
C1CN=C(N1)C2=NC3=CC=CC=C3C=C2.Cl
Target:
Imidazoline Receptor

References

1. Mirzaei N, et al. Imidazoline ligand BU224 reverses cognitive deficits, reduces microgliosis and enhances synaptic connectivity in a mouse model of Alzheimer's disease. Br J Pharmacol. 2021 Feb;178(3):654-671. 2. Min JW, et al. Gender difference in epileptogenic effects of 2-BFI and BU224 in mice. Eur J Pharmacol. 2013 Oct 15;718(1-3):81-6.