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TargetMol
Product Code: TAR-T2262
Supplier: TargetMol
CodeSizePrice
TAR-T2262-1mg1mg£95.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2262-2mg2mg£106.00
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TAR-T2262-5mg5mg£128.00
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Quantity:
TAR-T2262-1mL1 mL * 10 mM (in DMSO)£134.00
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Quantity:
TAR-T2262-10mg10mg£161.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2262-25mg25mg£254.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2262-50mg50mg£362.00
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Quantity:
TAR-T2262-100mg100mg£510.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
CHF5074, a γ-secretase modulator, reduces Aβ42/40 secretion (IC50: 3.6/18.4 μM).
CAS:
749269-83-8
Formula:
C16H11Cl2FO2
Molecular Weight:
325.16
Pathway:
Neuroscience; Proteases/Proteasome; Stem Cells
Purity:
0.98
SMILES:
OC(=O)C1(CC1)c1ccc(c(F)c1)-c1ccc(Cl)c(Cl)c1
Target:
Beta Amyloid; Gamma-secretase

References

1. Imbimbo BP, et al. J Pharmacol Exp Ther. 2007 Dec;323(3):822-30. 2. Ronsisvalle N, et al. Curr Alzheimer Res. 2014;11(7):714-24.