SGX-523

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TargetMol
Product Code: TAR-T2293
Supplier: TargetMol
CodeSizePrice
TAR-T2293-1mg1mg£106.00
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TAR-T2293-2mg2mg£119.00
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TAR-T2293-5mg5mg£149.00
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TAR-T2293-10mg10mg£185.00
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TAR-T2293-25mg25mg£306.00
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TAR-T2293-50mg50mg£450.00
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TAR-T2293-100mg100mg£627.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
SGX-523 is a selective Met inhibitor (IC50: 4 nM), no inhibitory to Abl, BRAFV599E, p38α, and c-Raf.
CAS:
1022150-57-7
Formula:
C18H13N7S
Molecular Weight:
359.41
Pathway:
MAPK; Tyrosine Kinase/Adaptors; Cytoskeletal Signaling; Angiogenesis
Purity:
0.996
SMILES:
Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncccc4c3)n2n1
Target:
Raf; p38 MAPK; c-Met/HGFR; Bcr-Abl

References

1. Buchanan SG, et al. Mol Cancer Ther, 2009, 8(12), 3181-3190.