HS-173

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TargetMol
Product Code: TAR-T2308
Supplier: TargetMol
CodeSizePrice
TAR-T2308-1mg1mg£98.00
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TAR-T2308-2mg2mg£109.00
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TAR-T2308-5mg5mg£132.00
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TAR-T2308-1mL1 mL * 10 mM (in DMSO)£138.00
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TAR-T2308-10mg10mg£181.00
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TAR-T2308-25mg25mg£300.00
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TAR-T2308-50mg50mg£425.00
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TAR-T2308-100mg100mg£531.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
HS-173 is an effective PI3Kα inhibitor (IC50: 0.8 nM).
CAS:
1276110-06-5
Formula:
C21H18N4O4S
Molecular Weight:
422.46
Pathway:
Apoptosis; PI3K/Akt/mTOR signaling
Purity:
0.9947
SMILES:
CCOC(=O)c1cnc2ccc(cn12)-c1cncc(NS(=O)(=O)c2ccccc2)c1
Target:
Apoptosis; PI3K

References

1. Kim O, et al. J Med Chem. 2011, 54(7), 2455-2466. 2. Lee H, et al. Cancer Lett. 2013, 328(1), 152-159. 3. Yun SM, et al. Cancer Lett. 2013, 331(2), 250-261. 4. Son MK, et al. Sci Rep. 2013, 3, 3470.