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TargetMol
Product Code: TAR-T2351
Supplier: TargetMol
CodeSizePrice
TAR-T2351-1mg1mg£107.00
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TAR-T2351-5mg5mg£148.00
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TAR-T2351-1mL1 mL * 10 mM (in DMSO)£172.00
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Quantity:
TAR-T2351-10mg10mg£202.00
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Quantity:
TAR-T2351-25mg25mg£310.00
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TAR-T2351-50mg50mg£467.00
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Quantity:
TAR-T2351-100mg100mg£550.00
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TAR-T2351-200mg200mg£764.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
TAK875 is a potent, selective and orally bioavailable GPR40 agonist.
CAS:
1000413-72-8
Formula:
C29H32O7S
Molecular Weight:
524.63
Pathway:
GPCR/G Protein; Endocrinology/Hormones
Purity:
0.9982
SMILES:
Cc1cc(OCCCS(C)(=O)=O)cc(C)c1-c1cccc(COc2ccc3[C@H](CC(O)=O)COc3c2)c1
Target:
GPR

References

1. Tsujihata Y,et al. TAK-875, an orally available G protein-coupled receptor 40/free fatty acid receptor 1 agonist, enhances glucose-dependent insulin secretion and improves both postprandial and fasting hyperglycemia in type 2 diabetic rats.J Pharmacol Exp 2. Yoshiyuki Tsujihata, et al. TAK-875, an Orally Available GPR40/FFA1 Agonist Enhances Glucose-Dependent Insulin Secretion and Improves Both Postprandial and Fasting Hyperglycemia in Type 2 Diabetic Rats. JPET July 13, 2011