Tucatinib

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TargetMol
Product Code: TAR-T2364
Supplier: TargetMol
CodeSizePrice
TAR-T2364-5mg5mg£107.00
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TAR-T2364-10mg10mg£128.00
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TAR-T2364-1mL1 mL * 10 mM (in DMSO)£134.00
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TAR-T2364-25mg25mg£172.00
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TAR-T2364-50mg50mg£229.00
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TAR-T2364-100mg100mg£367.00
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TAR-T2364-500mg500mg£768.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Irbinitinib(ARRY-380; ONT-380) is a potent and selective HER2 inhibitor (IC50: 8 nM).
CAS:
937263-43-9
Formula:
C26H24N8O2
Molecular Weight:
480.532
Pathway:
JAK/STAT signaling; Angiogenesis; Tyrosine Kinase/Adaptors
Purity:
0.9996
SMILES:
Cc1cc(Nc2ncnc3ccc(NC4=NC(C)(C)CO4)cc23)ccc1Oc1ccn2ncnc2c1
Target:
EGFR; HER

References

1. P Lee, et al. Cancer Research(Poster Session Abstracts). 2009, 69(24 Suppl):Abstract nr 5104. 2. SL Moulder, et al. AACR-NCI-EORTC. Nov 12-16, 2011, Abstract#A143.