Liproxstatin-1

TargetMol
Product Code: TAR-T2376
Supplier: TargetMol
CodeSizePrice
TAR-T2376-2mg2mg£109.00
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Quantity:
TAR-T2376-1mL1 mL * 10 mM (in DMSO)£136.00
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Quantity:
TAR-T2376-5mg5mg£136.00
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Quantity:
TAR-T2376-10mg10mg£182.00
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Quantity:
TAR-T2376-25mg25mg£322.00
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Quantity:
TAR-T2376-50mg50mg£472.00
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Quantity:
TAR-T2376-100mg100mg£511.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Liproxstatin-1 is a potent ferroptosis inhibitor.
CAS:
950455-15-9
Formula:
C19H21ClN4
Molecular Weight:
340.86
Pathway:
Cell Cycle/Checkpoint; Apoptosis
Purity:
0.9944
SMILES:
Clc1cccc(CNC2=Nc3ccccc3NC22CCNCC2)c1
Target:
Ferroptosis

References

1. Friedmann Angeli JP, et al. Nat Cell Biol. 2014, 16(12):1180-1191. 2. Su G, Yang W, Wang S, et al. SIRT1-autophagy axis inhibits excess iron-induced ferroptosis of foam cells and subsequently increases IL-1? and IL-18[J]. Biochemical and Biophysical Research Communications. 2021, 561: 33-39. 3. Rui T, Wang H, Li Q, et al. Deletion of ferritin H in neurons counteracts the protective effect of melatonin against traumatic brain injury?induced ferroptosis[J]. Journal of Pineal Research. 2020: e12704.