FG-2216

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TargetMol
Product Code: TAR-T2445
Supplier: TargetMol
CodeSizePrice
TAR-T2445-2mg2mg£97.00
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TAR-T2445-5mg5mg£112.00
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TAR-T2445-1mL1 mL * 10 mM (in DMSO)£114.00
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TAR-T2445-10mg10mg£142.00
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TAR-T2445-25mg25mg£213.00
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TAR-T2445-50mg50mg£280.00
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TAR-T2445-100mg100mg£381.00
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TAR-T2445-500mg500mg£812.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
FG-2216 is a potent HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme (IC50: 3.9 uM); orally bioavailable and induced reversible and significant Epo induction in vivo.
CAS:
223387-75-5
Formula:
C12H9ClN2O4
Molecular Weight:
280.66
Pathway:
Chromatin/Epigenetic; Metabolism
Purity:
0.99
SMILES:
OC(=O)CNC(=O)c1nc(Cl)c2ccccc2c1O
Target:
HIF/HIF Prolyl-Hydroxylase

References

1. Hong YR, et al. Bioorg Med Chem Lett. 2013, 23(21), 5953-5957. 2. Hsieh MM, et al. Blood. 2007, 110(6), 2140-2147.