SANT-1

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TargetMol
Product Code: TAR-T2450
Supplier: TargetMol
CodeSizePrice
TAR-T2450-2mg2mg£95.00
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TAR-T2450-5mg5mg£109.00
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Quantity:
TAR-T2450-1mL1 mL * 10 mM (in DMSO)£112.00
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Quantity:
TAR-T2450-10mg10mg£132.00
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Quantity:
TAR-T2450-25mg25mg£173.00
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TAR-T2450-50mg50mg£237.00
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TAR-T2450-100mg100mg£367.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
SANT-1 directly binds to Smoothened (Smo) receptor (Kd: 1.2 nM) and inhibits Smo agonist effects (IC50: 20 nM).
CAS:
304909-07-7
Formula:
C23H27N5
Molecular Weight:
373.504
Pathway:
Stem Cells; GPCR/G Protein
Purity:
0.9984
SMILES:
Cc1nn(c(C)c1C=NN1CCN(Cc2ccccc2)CC1)-c1ccccc1
Target:
Hedgehog/Smoothened; Smo

References

1. James K. Chen, et al. Proc Natl Acad Sci U S A, 2002, 99(22), 14071-14076. 2. Wilson CW, et al. PLoS One. 2009;4(4):e5182. 3. Chun SG, et al. Cancer Biol Ther, 2009, 8(14), 1328-1339.