Tivozanib

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TargetMol
Product Code: TAR-T2456
Supplier: TargetMol
CodeSizePrice
TAR-T2456-2mg2mg£98.00
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TAR-T2456-5mg5mg£115.00
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TAR-T2456-1mL1 mL * 10 mM (in DMSO)£119.00
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TAR-T2456-10mg10mg£132.00
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TAR-T2456-25mg25mg£187.00
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TAR-T2456-50mg50mg£273.00
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TAR-T2456-100mg100mg£432.00
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TAR-T2456-200mg200mg£603.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Tivozanib is an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with potential antiangiogenic and antineoplastic activities.
CAS:
475108-18-0
Formula:
C22H19ClN4O5
Molecular Weight:
454.87
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis
Purity:
0.9823
SMILES:
COc1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)on4)c(Cl)c3)c2cc1OC
Target:
VEGFR; PDGFR; Ephrin Receptor

References

1. Nakamura K, et al. Cancer Res, 2006, 66(18), 9134-9142. 2. Taguchi E, et al. Cancer Sci, 2008, 99(3), 623-630.