R243

TargetMol
Product Code: TAR-T24700
Supplier: TargetMol
CodeSizePrice
TAR-T24700-1mg1mg£99.00
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Quantity:
TAR-T24700-2mg2mg£111.00
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TAR-T24700-5mg5mg£132.00
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Quantity:
TAR-T24700-1mL1 mL * 10 mM (in DMSO)£140.00
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Quantity:
TAR-T24700-10mg10mg£172.00
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Quantity:
TAR-T24700-25mg25mg£256.00
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Quantity:
TAR-T24700-50mg50mg£367.00
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TAR-T24700-100mg100mg£511.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1

Further Information

Bioactivity:
R243 is CCR8 signaling and chemotaxis inhibitor.
CAS:
688352-84-3
Formula:
C21H27NO4
Molecular Weight:
357.45
Pathway:
Immunology/Inflammation; Microbiology/Virology
Purity:
0.9786
SMILES:
C(CN1COc2cc3OCOc3cc2C1)OC12CC3CC(CC(C3)C1)C2
Target:
CCR

References

1. Berenguer J, Lagerweij T, Zhao XW, et al. Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8. J Extracell Vesicles. 2018 Mar 13;7(1):1446660. doi: 10.1080/20013078.2018.1446660. eCollection 2018. PubMed PMID: 29696074. 2. Huber DA, Schreihofer AM. Exaggerated sympathoexcitatory reflexes develop with changes in the rostral ventrolateral medulla in obese Zucker rats. Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R243-53. doi: 10.1152/ajpregu.00085.2016. Epub 2016 Jun 8. PubMed PMID: 27280427. 3. Wan H, Otsuka Y, Gao ZQ, Wei Y, Chen Z, Masuda M, Yonesaki T, Zhang H, Dong YH. Structural insights into the inhibition mechanism of bacterial toxin LsoA by bacteriophage antitoxin Dmd. Mol Microbiol. 2016 Sep;101(5):757-69. doi: 10.1111/mmi.13420. Epub 2016 Jun 2. PubMed PMID: 27169810. 4. Richards MB, Soares P, Torroni A. Palaeogenomics: Mitogenomes and Migrations in Europe's Past. Curr Biol. 2016 Mar 21;26(6):R243-6. doi: 10.1016/j.cub.2016.01.044. PubMed PMID: 27003890.