Althiomycin
| Code | Size | Price |
|---|
| TAR-T25060-2mg | 2mg | £1,154.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Althiomycin is an antibiotic.
CAS:
12656-40-5
Formula:
C16H17N5O6S2
Molecular Weight:
439.46
Purity:
0.98
SMILES:
COC1=CC(=O)N(C1)C(=O)[C@H]1CSC(=N1)[C@H](CO)NC(=O)c1csc(C=NO)n1
References
1. Gerc AJ, Song L, Challis GL, Stanley-Wall NR, Coulthurst SJ. The insect pathogen Serratia marcescens Db10 uses a hybrid non-ribosomal peptide synthetase-polyketide synthase to produce the antibiotic althiomycin. PLoS One. 2012;7(9):e44673. doi: 10.1371/journal.pone.0044673. Epub 2012 Sep 18. PubMed PMID: 23028578; PubMed Central PMCID: PMC3445576.
2. Gerc AJ, Stanley-Wall NR, Coulthurst SJ. Role of the phosphopantetheinyltransferase enzyme, PswP, in the biosynthesis of antimicrobial secondary metabolites by Serratia marcescens Db10. Microbiology. 2014 Aug;160(Pt 8):1609-17. doi: 10.1099/mic.0.078576-0. Epub 2014 May 20. PubMed PMID: 24847000; PubMed Central PMCID: PMC4117218.
3. Cortina NS, Revermann O, Krug D, M?ller R. Identification and characterization of the althiomycin biosynthetic gene cluster in Myxococcus xanthus DK897. Chembiochem. 2011 Jun 14;12(9):1411-6. doi: 10.1002/cbic.201100154. Epub 2011 May 27. PubMed PMID: 21626639.
4. Zarantonello P, Leslie CP, Ferritto R, Kazmierski WM. Total synthesis and semi-synthetic approaches to analogues of antibacterial natural product althiomycin. Bioorg Med Chem Lett. 2002 Feb 25;12(4):561-5. PubMed PMID: 11844672.