Etravirine

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TargetMol
Product Code: TAR-T2551
Supplier: TargetMol
CodeSizePrice
TAR-T2551-1mg1mg£98.00
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TAR-T2551-2mg2mg£109.00
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TAR-T2551-5mg5mg£133.00
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TAR-T2551-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T2551-10mg10mg£169.00
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TAR-T2551-25mg25mg£230.00
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TAR-T2551-50mg50mg£306.00
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TAR-T2551-100mg100mg£394.00
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TAR-T2551-200mg200mg£481.00
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TAR-T2551-500mg500mg£736.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Etravirine is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. Etravirine is designed to be active against HIV isolates with mutations that confer resistance to the two most commonly prescribed first-generation NNRTIs. It can bind the enzyme reverse transcriptase (RT) in multiple conformations, both for native and mutant RT, thereby blocking the enzymatic activity of RT.
CAS:
269055-15-4
Formula:
C20H15BrN6O
Molecular Weight:
435.285
Pathway:
Proteases/Proteasome; Microbiology/Virology
Purity:
0.9956
SMILES:
Cc1cc(cc(C)c1Oc1nc(Nc2ccc(cc2)C#N)nc(N)c1Br)C#N
Target:
HIV Protease; Reverse Transcriptase

References

1. Das K, et al. J Med Chem, 2004, 47(10), 2550-2560. 2. Andries K, et al. Antimicrob Agents Chemother, 2004, 48(12), 4680-4686. 3. Lazzarin A, et al. Lancet, 2007, 370(9581), 39-48. 4. Fical L. V?voj UHPLC-MS/MS metody pro anal?zu vybran?ch antivirotik v HILIC a RP m?du[J]. 2020