A-1210477

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TargetMol
Product Code: TAR-T2632
Supplier: TargetMol
CodeSizePrice
TAR-T2632-2mg2mg£98.00
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TAR-T2632-5mg5mg£115.00
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TAR-T2632-10mg10mg£148.00
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TAR-T2632-25mg25mg£201.00
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TAR-T2632-50mg50mg£302.00
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TAR-T2632-100mg100mg£430.00
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TAR-T2632-500mg500mg£863.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
A-1210477 is an effective and specific MCL-1 and Bcl-2 inhibitor (Ki/IC50: 0.454/26.2 nM).
CAS:
1668553-26-1
Formula:
C46H55N7O7S
Molecular Weight:
850.05
Pathway:
Apoptosis
Purity:
0.9976
SMILES:
CN(C)S(=O)(=O)N1CCN(CC1)c1ccc(OCc2c(c(C)nn2C)-c2cccc3c(CCCOc4cccc5ccccc45)c(C(O)=O)n(CCN4CCOCC4)c23)cc1
Target:
Apoptosis; BCL

References

1. Leverson JD, et al. Cell Death Dis. 2015, 6:e1590. doi: 10.1038/cddis.2014.561. 2. Xiao Y, et al. Mol Cancer Ther. 2015, 14(8), 1837-1847. 3. Phillips DC, et al. Blood Cancer J. 2015, 5:e368. doi: 10.1038/bcj.2015.88.