GSK2656157

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TargetMol
Product Code: TAR-T2654
Supplier: TargetMol
CodeSizePrice
TAR-T2654-2mg2mg£96.00
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TAR-T2654-5mg5mg£111.00
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TAR-T2654-10mg10mg£130.00
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TAR-T2654-1mL1 mL * 10 mM (in DMSO)£136.00
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TAR-T2654-25mg25mg£187.00
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Quantity:
TAR-T2654-50mg50mg£289.00
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TAR-T2654-100mg100mg£466.00
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TAR-T2654-200mg200mg£605.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
GSK2656157 is a highly specific and ATP-competitive PERK inhibitor (IC50: 0.9 nM) in a cell-free assay. The selectivty is 500-fold higher against a panel of 300 kinases.
CAS:
1337532-29-2
Formula:
C23H21FN6O
Molecular Weight:
416.46
Pathway:
Apoptosis; Autophagy
Purity:
0.9989
SMILES:
Cc1cccc(CC(=O)N2CCc3c2ccc(-c2cn(C)c4ncnc(N)c24)c3F)n1
Target:
Apoptosis; PERK; Autophagy

References

1. Atkins C, et al. Cancer Res, 2013, 73(6), 1993-2002.