TGX-221

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TargetMol
Product Code: TAR-T2661
Supplier: TargetMol
CodeSizePrice
TAR-T2661-1mg1mg£96.00
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TAR-T2661-2mg2mg£107.00
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TAR-T2661-5mg5mg£125.00
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TAR-T2661-1mL1 mL * 10 mM (in DMSO)£130.00
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Quantity:
TAR-T2661-10mg10mg£165.00
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TAR-T2661-25mg25mg£254.00
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Quantity:
TAR-T2661-50mg50mg£374.00
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TAR-T2661-100mg100mg£544.00
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Quantity:
TAR-T2661-500mg500mg£1,083.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
TGX-221, an effective, specific, and cell membrane permeable inhibitor of the PI3K p110β catalytic subunit, is utilized for cancer treatment.
CAS:
663619-89-4
Formula:
C21H24N4O2
Molecular Weight:
364.449
Pathway:
PI3K/Akt/mTOR signaling
Purity:
0.998
SMILES:
CC(Nc1ccccc1)c1cc(C)cn2c1nc(cc2=O)N1CCOCC1
Target:
PI3K

References

1. Chaussade C, et al. Biochem J. 2007, 404(3), 449-458. 2. Straub A, et al. Thromb Haemost. 2008, 99(3), 609-615. 3. Lu XY, et al. Appl Microbiol Biotechnol. 2011, 89(5), 1423-1433. 4. Bird JE, et al. Thromb Res. 2011, 127(6), 560-564. 5. Jackson SP, et al. Nat Med. 2005, 11(5), 507-514.