4EGI-1

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TargetMol
Product Code: TAR-T2665
Supplier: TargetMol
CodeSizePrice
TAR-T2665-1mg1mg£100.00
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TAR-T2665-2mg2mg£111.00
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TAR-T2665-5mg5mg£143.00
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TAR-T2665-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T2665-10mg10mg£164.00
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TAR-T2665-25mg25mg£256.00
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TAR-T2665-50mg50mg£367.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
4EGI-1, a competitive eIF4E/eIF4 g interaction inhibitor, binds to eIF4E(KD=25 μM).
CAS:
315706-13-9
Formula:
C18H12Cl2N4O4S
Molecular Weight:
451.28
Pathway:
Apoptosis; Autophagy
Purity:
0.9912
SMILES:
OC(=O)C(Cc1ccccc1[N+]([O-])=O)=NNc1nc(cs1)-c1ccc(Cl)c(Cl)c1
Target:
Apoptosis; PERK; Autophagy

References

1. Moerke NJ, et al. Cell. 2007, 128(2), 257-267. 2. Fan S, et al. Neoplasia. 2010, 12(4), 346-356. 3. Willimott S, et al. Clin Cancer Res. 2013, 19(12), 3212-3223.