TG100-115

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TargetMol
Product Code: TAR-T2672
Supplier: TargetMol
CodeSizePrice
TAR-T2672-1mg1mg£99.00
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TAR-T2672-5mg5mg£132.00
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TAR-T2672-1mL1 mL * 10 mM (in DMSO)£138.00
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TAR-T2672-10mg10mg£164.00
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TAR-T2672-25mg25mg£249.00
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TAR-T2672-50mg50mg£389.00
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TAR-T2672-100mg100mg£568.00
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TAR-T2672-500mg500mg£1,099.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
TG100-115 is a PI3Kγ/δ inhibitor (IC50: 83/235 nM), with fewer effects on PI3Kα/β.
CAS:
677297-51-7
Formula:
C18H14N6O2
Molecular Weight:
346.35
Pathway:
PI3K/Akt/mTOR signaling
Purity:
0.99
SMILES:
Nc1nc(N)c2nc(-c3cccc(O)c3)c(nc2n1)-c1cccc(O)c1
Target:
PI3K

References

1. Doukas J, et al. Proc Natl Acad Sci U S A, 2006, 103(52), 19866-119871. 2. Palanki MS, et al. J Med Chem, 2007, 50(18), 4279-4294. 3. Acevedo LM, et al. Blood, 2008, 111(5), 2674-2680. 4. Doukas J, et al. J Pharmacol Exp Ther, 2009, 328(3), 758-765.