Spirolaxine
| Code | Size | Price |
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| TAR-T28834-2mg | 2mg | £903.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Spirolaxine, a natural product isolated from Sporotrichum laxum ATCC 15155, has shown a variety of biological activities including promising anti-Helicobacter pylori property.
CAS:
126382-01-2
Formula:
C23H32O6
Molecular Weight:
404.503
Purity:
0.98
SMILES:
COc1cc(O)cc2[C@@H](CCCCC[C@@H]3CCC[C@]4(CC[C@@H](C)O4)O3)OC(=O)c12
References
1. Sun L, Wang S, Zhang S, Yu D, Qin Y, Huang H, Wang W, Zhan J. Identification of a type III polyketide synthase involved in the biosynthesis of spirolaxine. Appl Microbiol Biotechnol. 2016 Aug;100(16):7103-13. doi: 10.1007/s00253-016-7444-5. Epub 2016 Mar 29. PubMed PMID: 27023915.
2. Wang S, Zhang S, Zhou T, Zhan J. Three new resorcylic acid derivatives from Sporotrichum laxum. Bioorg Med Chem Lett. 2013 Nov 1;23(21):5806-9. doi: 10.1016/j.bmcl.2013.08.109. Epub 2013 Sep 7. PubMed PMID: 24070784; PubMed Central PMCID: PMC3825103.
3. Yadav JS, Sreenivas M, Srinivas Reddy A, Subba Reddy BV. A practical total synthesis of (+)-spirolaxine methyl ether. J Org Chem. 2010 Dec 3;75(23):8307-10. doi: 10.1021/jo1016647. Epub 2010 Nov 8. PubMed PMID: 21058660.
4. Sperry J, Liu YC, Brimble MA. Synthesis of natural products containing spiroketals via intramolecular hydrogen abstraction. Org Biomol Chem. 2010 Jan 7;8(1):29-38. doi: 10.1039/b916041h. Epub 2009 Oct 7. PubMed PMID: 20024126.