TargetMol

Oxysophoridine

Product Code:
 
TAR-T2S1008
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T2S1008-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T2S1008-20mg20mg£119.00
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Further Information

Bioactivity:
Oxysophoridine has a protective effect on focal cerebral ischemic injury through antioxidant and anti-apoptotic mechanisms; it may be a potential neuroprotective agent for cerebral ischemia injury, that the effect may be due to its ability to inhibit oxidative stress and expression of the N-methyl-D-aspartate receptor subunit NR1.Oxysophoridine ameliorates cardiac damage in a rat model of AMI and that this cardioprotection may be linked with its anti-oxidative, anti-apoptotic and anti-inflammatory properties.
CAS:
54809-74-4
Formula:
C15H24N2O2
Molecular Weight:
264.369
Pathway:
oxidation-reduction; Apoptosis
Purity:
1
SMILES:
[O-][N+]12CCC[C@@H]3CN4[C@H](CCCC4=O)[C@@H](CCC1)[C@@H]23
Target:
Apoptosis; Antioxidant

References

1. Rui C , Yuxiang L , Ning J , et al. Anti-apoptotic and Neuroprotective Effects of Oxysophoridine on Cerebral Ischemia Both In Vivo and In Vitro[J]. Planta Medica, 2013, 79(11):916-923. 2. Cong, Meng, Chuan, et al. Oxysophoridine attenuates the injury caused by acute myocardial infarction in rats through anti-oxidative, anti-inflammatory and anti-apoptotic pathways.[J]. Molecular Medicine Reports, 2015. 3. Wang T F , Lei Z , Li Y X , et al. Oxysophoridine Protects Against Focal Cerebral Ischemic Injury by Inhibiting Oxidative Stress and Apoptosis in Mice[J]. Neurochemical Research, 2013, 38(11):2408-2417.