CZC-25146

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TargetMol
Product Code: TAR-T3053
Supplier: TargetMol
CodeSizePrice
TAR-T3053-1mg1mg£95.00
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TAR-T3053-2mg2mg£106.00
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TAR-T3053-5mg5mg£125.00
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TAR-T3053-1mL1 mL * 10 mM (in DMSO)£131.00
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TAR-T3053-10mg10mg£164.00
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TAR-T3053-25mg25mg£274.00
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TAR-T3053-50mg50mg£438.00
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TAR-T3053-100mg100mg£611.00
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TAR-T3053-500mg500mg£1,219.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
CZC-25146 is an effective, specific and metabolically stable LRRK2 inhibitor with IC50 of 4.76/6.87 nM for wild-type LRRK2(Leucine-rich repeat kinase-2) and G2019S LRRK2, respectively.
CAS:
1191911-26-8
Formula:
C22H25FN6O4S
Molecular Weight:
488.54
Pathway:
Autophagy
Purity:
0.982
SMILES:
COc1cc(ccc1Nc1ncc(F)c(Nc2ccccc2NS(C)(=O)=O)n1)N1CCOCC1
Target:
LRRK2

References

1. Ramsden N, et al. ACS Chem Biol. 2011 Oct 21;6(10):1021-8.