TG101209

Contact us
TargetMol
Product Code: TAR-T3065
Supplier: TargetMol
CodeSizePrice
TAR-T3065-2mg2mg£103.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3065-5mg5mg£119.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3065-1mL1 mL * 10 mM (in DMSO)£124.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3065-10mg10mg£139.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3065-25mg25mg£157.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3065-50mg50mg£172.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3065-100mg100mg£237.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1
❮❯

Documents

Further Information

Bioactivity:
TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.
CAS:
936091-14-4
Formula:
C26H35N7O2S
Molecular Weight:
509.67
Pathway:
Angiogenesis; Tyrosine Kinase/Adaptors; Stem Cells; Apoptosis; JAK/STAT signaling; Chromatin/Epigenetic; Autophagy
Purity:
0.99
SMILES:
CN1CCN(CC1)c1ccc(Nc2ncc(C)c(Nc3cccc(c3)S(=O)(=O)NC(C)(C)C)n2)cc1
Target:
Apoptosis; FLT; c-RET; JAK; Autophagy

References

1. Pardanani A, et al, Leukemia, 2007, 21(8), 1658-1668. 2. Ma AC, et al, Exp Hematol, 2009, 37(12), 1379-1386. 3. Sun Y, et al, J Thorac Oncol, 2011, 6(4), 699-706. 4. Cuesta-Dominquez A, et al, PLoS One, 2012, 7(2), e32451. 5. Wang Y, et al, Blood, 2009, 114(24), 5024-5033.