SGI-1776

TargetMol
Product Code: TAR-T3078
Supplier: TargetMol
CodeSizePrice
TAR-T3078-2mg2mg£109.00
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TAR-T3078-5mg5mg£149.00
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TAR-T3078-1mL1 mL * 10 mM (in DMSO)£151.00
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TAR-T3078-10mg10mg£211.00
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TAR-T3078-25mg25mg£328.00
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TAR-T3078-50mg50mg£441.00
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Quantity:
TAR-T3078-100mg100mg£545.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
SGI-1776 has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.
CAS:
1025065-69-3
Formula:
C20H22F3N5O
Molecular Weight:
405.425
Pathway:
Angiogenesis; JAK/STAT signaling; Chromatin/Epigenetic; Autophagy; Apoptosis; Tyrosine Kinase/Adaptors
Purity:
0.9984
SMILES:
CN1CCC(CNc2ccc3ncc(-c4cccc(OC(F)(F)F)c4)n3n2)CC1
Target:
Apoptosis; FLT; Pim; Autophagy

References

1. Chen LS, et al. Blood, 2011, 118(3), 693-702. 2. Chen LS, et al. Blood, 2009, 114(19), 4150-7. 3. Batra V, et al. Pediatr Blood Cancer, 2012, 59(4), 749-752.