GSK1838705A

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TargetMol
Product Code: TAR-T3079
Supplier: TargetMol
CodeSizePrice
TAR-T3079-1mg1mg£98.00
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TAR-T3079-2mg2mg£109.00
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TAR-T3079-5mg5mg£132.00
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TAR-T3079-1mL1 mL * 10 mM (in DMSO)£142.00
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TAR-T3079-10mg10mg£177.00
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TAR-T3079-25mg25mg£295.00
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TAR-T3079-50mg50mg£477.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
GSK1838705A is an effective IGF-1R inhibitor (IC50: 2.0 nM), modestly potent to IR (IC50: 1.6 nM) and ALK (IC50: 0.5 nM), respectively, and little inhibition to other protein kinases.
CAS:
1116235-97-2
Formula:
C27H29FN8O3
Molecular Weight:
532.58
Pathway:
Angiogenesis; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors; MAPK
Purity:
0.9889
SMILES:
CNC(=O)c1c(F)cccc1Nc1nc(Nc2cc3N(CCc3cc2OC)C(=O)CN(C)C)nc2[nH]ccc12
Target:
IGF-1R; JNK; S6 Kinase; ALK

References

1. Sabbatini P, et al. Mol Cancer Ther. 2009, 8(10), 2811-2820.