VX-11e

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TargetMol
Product Code: TAR-T3166
Supplier: TargetMol
CodeSizePrice
TAR-T3166-2mg2mg£111.00
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TAR-T3166-5mg5mg£143.00
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TAR-T3166-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-T3166-10mg10mg£170.00
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TAR-T3166-25mg25mg£262.00
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TAR-T3166-50mg50mg£374.00
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TAR-T3166-100mg100mg£540.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
VX-11e is a potent, selective, and orally bioavailable ERK(Extracellular Signal-Regulated Kinase) inhibitor; antitumor agent.
CAS:
896720-20-0
Formula:
C24H20Cl2FN5O2
Molecular Weight:
500.35
Pathway:
Cell Cycle/Checkpoint; Angiogenesis; MAPK; Chromatin/Epigenetic; Stem Cells; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
Purity:
0.9967
SMILES:
Cc1cnc(Nc2ccc(cc2Cl)F)nc1c1cc(C(=O)N[C@H](CO)c2cccc(c2)Cl)[nH]c1
Target:
ERK; GSK-3; FLT; CDK; Aurora Kinase

References

1. Aronov AM, et al. J Med Chem. 2009, 52(20), 6362-6368. 2. Krepler C, et al. Clin Cancer Res. 2015. pii: clincanres.1762. 2015