GNF-7

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TargetMol
Product Code: TAR-T3196
Supplier: TargetMol
CodeSizePrice
TAR-T3196-1mg1mg£100.00
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TAR-T3196-2mg2mg£113.00
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TAR-T3196-5mg5mg£140.00
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TAR-T3196-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-T3196-10mg10mg£189.00
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TAR-T3196-25mg25mg£309.00
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TAR-T3196-50mg50mg£502.00
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TAR-T3196-100mg100mg£701.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respectively.
CAS:
839706-07-9
Formula:
C28H24F3N7O2
Molecular Weight:
547.542
Pathway:
Angiogenesis; Neuroscience; Tyrosine Kinase/Adaptors; Cytoskeletal Signaling
Purity:
0.9947
SMILES:
CN1C(=O)N(Cc2cnc(Nc3ccc(C)nc3)nc12)c1cc(NC(=O)c2cccc(c2)C(F)(F)F)ccc1C
Target:
Bcr-Abl; ACK; AChR

References

1. Choi HG, et al. J Med Chem. 2010, 53(15), 5439-5448. 2. Nonami A, et al. Blood. 2015, 125(20), 3133-3143.