Ezutromid

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TargetMol
Product Code: TAR-T3424
Supplier: TargetMol
CodeSizePrice
TAR-T3424-1mg1mg£98.00
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TAR-T3424-2mg2mg£109.00
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TAR-T3424-5mg5mg£135.00
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TAR-T3424-1mL1 mL * 10 mM (in DMSO)£142.00
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TAR-T3424-10mg10mg£173.00
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TAR-T3424-25mg25mg£282.00
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TAR-T3424-50mg50mg£409.00
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TAR-T3424-100mg100mg£615.00
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TAR-T3424-500mg500mg£1,179.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Ezutromid is a translation modulator of Small utrophin (EC50: 0.4 uM). Ezutromid is an orally bioavailable small molecule that transcriptionally upregulates the utrophin gene, increasing both utrophin mRNA and protein. Through this action, Ezutromid increases muscle function in dystrophin-deficient MDX mice, a mouse model of muscular dystrophy.
CAS:
945531-77-1
Formula:
C19H15NO3S
Molecular Weight:
337.39
Purity:
0.9847
SMILES:
CCS(=O)(=O)c1ccc2oc(nc2c1)-c1ccc2ccccc2c1

References

Guiraud S et al. Hum Mol Genet. 2015 Aug 1;24(15):4212-24.,www.ncbi.nlm.nih.gov/pubmed/25935002 Tinsley J et al. J Clin Pharmacol. 2015 Jun;55(6):698-707., Tinsley JM et al. PLoS One. 2011 May 6;6(5):e19189.,