CC-115

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TargetMol
Product Code: TAR-T3541
Supplier: TargetMol
CodeSizePrice
TAR-T3541-1mg1mg£98.00
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TAR-T3541-2mg2mg£109.00
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TAR-T3541-5mg5mg£132.00
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TAR-T3541-1mL1 mL * 10 mM (in DMSO)£141.00
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TAR-T3541-10mg10mg£172.00
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TAR-T3541-25mg25mg£262.00
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TAR-T3541-50mg50mg£412.00
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TAR-T3541-100mg100mg£575.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
CC-115 is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM).
CAS:
1228013-15-7
Formula:
C16H16N8O
Molecular Weight:
336.359
Pathway:
PI3K/Akt/mTOR signaling; DNA Damage/DNA Repair
Purity:
0.8679
SMILES:
CCN1C(=O)CNc2ncc(nc12)-c1ccc(nc1C)-c1ncn[nH]1
Target:
DNA-PK; PI3K; mTOR

References

Mortensen DS, et al. J Med Chem. 2015, 58(14):5599-608. Thijssen R, et al. Blood. 2016, 128(4):574-83.