Y16

TargetMol
Product Code: TAR-T3553
Supplier: TargetMol
CodeSizePrice
TAR-T3553-2mg2mg£106.00
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TAR-T3553-5mg5mg£125.00
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TAR-T3553-1mL1 mL * 10 mM (in DMSO)£132.00
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TAR-T3553-10mg10mg£166.00
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TAR-T3553-25mg25mg£229.00
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TAR-T3553-50mg50mg£309.00
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TAR-T3553-100mg100mg£430.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1

Further Information

Bioactivity:
Y16 is a G-protein?coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated signaling functions.
CAS:
429653-73-6
Formula:
C24H20N2O3
Molecular Weight:
384.435
Pathway:
Cell Cycle/Checkpoint; GPCR/G Protein; MAPK
Purity:
1
SMILES:
Cc1cccc(COc2cccc(C=C3C(=O)NN(C3=O)c3ccccc3)c2)c1
Target:
Rho; Ras

References

Yoneda T,et al. The antiproliferative effects of tyrosine kinase inhibitors tyrphostins on a human squamous cell carcinoma in vitro and in nude mice. Cancer Res. 1991 Aug 15;51(16):4430-5.