NIH-12848

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TargetMol
Product Code: TAR-T3556
Supplier: TargetMol
CodeSizePrice
TAR-T3556-1mg1mg£102.00
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TAR-T3556-2mg2mg£114.00
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TAR-T3556-5mg5mg£139.00
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TAR-T3556-1mL1 mL * 10 mM (in DMSO)£141.00
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TAR-T3556-10mg10mg£168.00
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TAR-T3556-25mg25mg£262.00
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TAR-T3556-50mg50mg£430.00
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TAR-T3556-100mg100mg£603.00
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TAR-T3556-500mg500mg£1,187.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
NIH-12848 is a putative inhibitor of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) with an IC50 of 1 μM.
CAS:
959551-10-1
Formula:
C20H14F3N3S
Molecular Weight:
385.41
Pathway:
PI3K/Akt/mTOR signaling
Purity:
0.9975
SMILES:
FC(F)(F)c1ccccc1-c1nc(NCc2cccs2)c2ccccc2n1
Target:
PI3K

References

Clarke, J., Giudici, M., Burke, J., Williams, R., Maloney, D., Marugan, J., & Irvine, R. (2015). The function of phosphatidylinositol 5-phosphate 4-kinase ? (PI5P4K?) explored using a specific inhibitor that targets the PI5P-binding site.?Biochemical Journal,?466(2), 359-367. doi: 10.1042/bj20141333