VU0357017 hydrochloride

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TargetMol
Product Code: TAR-T3619
Supplier: TargetMol
CodeSizePrice
TAR-T3619-2mg2mg£103.00
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TAR-T3619-5mg5mg£124.00
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TAR-T3619-1mL1 mL * 10 mM (in DMSO)£125.00
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TAR-T3619-10mg10mg£157.00
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TAR-T3619-25mg25mg£259.00
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TAR-T3619-50mg50mg£417.00
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TAR-T3619-100mg100mg£584.00
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TAR-T3619-500mg500mg£1,171.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
VU 0357017 hydrochloride is highly selective M1 agonists act at an allosteric site to activate the receptor (EC50: 477 ? 172 nM; Pec50: 6.37 ? 0.15).
CAS:
1135242-13-5
Formula:
C18H28ClN3O3
Molecular Weight:
369.89
Pathway:
Neuroscience
Purity:
0.999
SMILES:
Cl.CCOC(=O)N1CCC(CC1)NCCNC(=O)c1ccccc1C
Target:
AChR

References

Digby GJ, et al. ACS Chem Neurosci. 2012 Dec 19;3(12):1025-36. Lebois EP, et al. ACS Chem Neurosci. 2010;1(2):104-121. Digby GJ, et al. J Neurosci. 2012 Jun 20;32(25):8532-44. Sheffler DJ. et al.Bioorg Med Chem Lett. 2013 Jan 1;23(1):223-7.