Solcitinib

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TargetMol
Product Code: TAR-T3620
Supplier: TargetMol
CodeSizePrice
TAR-T3620-1mg1mg£95.00
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TAR-T3620-2mg2mg£106.00
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TAR-T3620-5mg5mg£128.00
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TAR-T3620-1mL1 mL * 10 mM (in DMSO)£134.00
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TAR-T3620-10mg10mg£148.00
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TAR-T3620-25mg25mg£193.00
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TAR-T3620-50mg50mg£230.00
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TAR-T3620-100mg100mg£334.00
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TAR-T3620-200mg200mg£495.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Solcitinib (GSK2586184, GLPG0778) is a JAK1 inhibitor. Solcitinib may be potentially used for the treatment of psoriasis, ulcerative colitis, and systemic lupus erythematosus.
CAS:
1206163-45-2
Formula:
C22H23N5O2
Molecular Weight:
389.45
Pathway:
Angiogenesis; JAK/STAT signaling; Chromatin/Epigenetic; Stem Cells
Purity:
0.9968
SMILES:
O=C(C=1C=CC(=CC1)C2=CC=CC3=NC(=NN32)NC(=O)C4CC4)N5CC(C)(C)C5
Target:
JAK

References

Chen C, Lu M, Lin S, et al. The nuclear gene rpl18 regulates erythroid maturation via JAK2-STAT3 signaling in zebrafish model of Diamond?Blackfan anemia[J]. Cell Death & Disease. 2020, 11(2): 1-11. Nakayamada S, et al. Expert Opin Pharmacother. 2016 Oct 3.; Chen C, Lu M, Lin S, et al. The nuclear gene rpl18 regulates erythroid maturation via JAK2-STAT3 signaling in zebrafish model of Diamond?Blackfan anemia. Cell Death & Disease. 2020, 11(2): 1-11 Kahl L, et al. Lupus. 2016 Apr 6. pii: 0961203316640910.;