TargetMol

Isobavachalcone

Product Code:
 
TAR-T3861
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3861-5mg5mg£115.00
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Quantity:
TAR-T3861-1mL1 mL * 10 mM (in DMSO)£119.00
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TAR-T3861-10mg10mg£145.00
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TAR-T3861-25mg25mg£229.00
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TAR-T3861-50mg50mg£306.00
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Quantity:
TAR-T3861-100mg100mg£422.00
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Quantity:
TAR-T3861-500mg500mg£859.00
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Quantity:
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Further Information

Bioactivity:
Isobavachalcone is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury in brain diseases associated with inflammation.
CAS:
20784-50-3
Formula:
C20H20O4
Molecular Weight:
324.376
Pathway:
Cytoskeletal Signaling; Apoptosis; Metabolism; Autophagy; Immunology/Inflammation; PI3K/Akt/mTOR signaling; ; NF-κb
Purity:
0.9976
SMILES:
CC(C)=CCc1c(O)ccc(C(=O)C=Cc2ccc(O)cc2)c1O
Target:
Apoptosis; Reactive Oxygen Species; Akt; Autophagy

References

Lee KM,et al. Isobavachalcone attenuates lipopolysaccharide-induced ICAM-1 expression in brain endothelial cells through blockade of toll-like receptor 4 signaling pathways. Eur J Pharmacol. 2015 May 5;754:11-8.