TargetMol

Vaccarin

Product Code:
 
TAR-T3881
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3881-1mL1 mL * 10 mM (in DMSO)£151.00
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Quantity:
TAR-T3881-20mg20mg£175.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
Vaccarin is a major flavonoid glycoside in Vaccariae semen, its biotransformation pathways involves methylation, hydroxylation, glycosylation and deglycosylation.
CAS:
53452-16-7
Formula:
C32H38O19
Molecular Weight:
726.637
Pathway:
Apoptosis; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling; Cytoskeletal Signaling
Purity:
0.9997
SMILES:
OC[C@H]1O[C@@H](Oc2ccc(cc2)-c2cc(=O)c3c(O)c([C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@@H]4OC[C@H](O)[C@H](O)[C@H]4O)c(O)cc3o2)[C@H](O)[C@@H](O)[C@@H]1O
Target:
Integrin; Akt; PERK; AMPK

References

Xie F,et al. Vaccarin attenuates the human EA.hy926 endothelial cell oxidative stress injury through inhibition of Notch signaling. Int J Mol Med. 2015 Jan;35(1):135-42. Xie F,et al. Vaccarin promotes endothelial cell proliferation in association with neovascularization in vitro and in vivo. Mol Med Rep. 2015 Jul;12(1):1131-6.