TargetMol

Saikosaponin C

Product Code:
 
TAR-T3914
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3914-1mg1mg£95.00
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TAR-T3914-5mg5mg£122.00
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TAR-T3914-10mg10mg£161.00
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TAR-T3914-25mg25mg£242.00
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TAR-T3914-50mg50mg£327.00
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TAR-T3914-100mg100mg£452.00
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This product comes from: United States.
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Further Information

Bioactivity:
Saikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation.
CAS:
20736-08-7
Formula:
C48H78O17
Molecular Weight:
927.135
Pathway:
Neuroscience; Proteases/Proteasome; Apoptosis
Purity:
0.9994
SMILES:
C[C@@H]1O[C@@H](O[C@@H]2[C@@H](CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)O[C@@H](O[C@H]3CC[C@@]4(C)[C@@H](CC[C@]5(C)[C@@H]4C=C[C@]46OC[C@@]7(CCC(C)(C)C[C@@H]47)[C@@H](O)C[C@@]56C)C3(C)C)[C@H](O)[C@H]2O)[C@H](O)[C@H](O)[C@H]1O
Target:
Beta Amyloid; Caspase

References

Yu KU1, Jang IS, Kang KH, Sung CK, Kim DH.Metabolism of saikosaponin c and naringin by human intestinal bacteria.Arch Pharm Res. 1997 Oct;20(5):420-4. Shyu KG1, Tsai SC, Wang BW, Liu YC, Lee CC.Saikosaponin C induces endothelial cells growth, migration and capillary tube formation.Life Sci. 2004 Dec 31;76(7):813-26. Lee TH1, Chang J2, Kim BM3. Saikosaponin C inhibits lipopolysaccharide-induced apoptosis by suppressing caspase-3 activation and subsequent degradation of focal adhesion kinase in human umbilical vein endothelial cells.Biochem Biophys Res Commun. 2014 Mar 14;445(3):615-21. Chiang LC1, Ng LT, Liu LT, Shieh DE, Lin CC.Cytotoxicity and anti-hepatitis B virus activities of saikosaponins from Bupleurum species.Planta Med. 2003 Aug;69(8):705-9.