Pentostatin
Code | Size | Price |
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TAR-T4006-2mg | 2mg | £100.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T4006-5mg | 5mg | £109.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T4006-1mL | 1 mL * 10 mM (in DMSO) | £123.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T4006-10mg | 10mg | £135.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T4006-25mg | 25mg | £226.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T4006-50mg | 50mg | £360.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T4006-100mg | 100mg | £500.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Pentostatin is an extremely effective and irreversible inhibitor of adenosine deaminase (Ki: 2.5 pM).
CAS:
53910-25-1
Formula:
C11H16N4O4
Molecular Weight:
268.273
Pathway:
Metabolism; GPCR/G Protein; Neuroscience
Purity:
0.98
SMILES:
OC[C@H]1O[C@H](C[C@@H]1O)n1cnc2[C@H](O)CN=CNc12
Target:
Adenosine deaminase; Adenosine Receptor
References
Dearden CE, Else M, Catovsky D.Long-term results for pentostatin and cladribine treatment of hairy cell leukemia.Leuk Lymphoma. 2011 Jun;52 Suppl 2:21-4.
Reynolds C., et al. Richards DA, Robbins GJ, Vellek M, Boehm KA, Zhan F, Asmar L.A Phase III trial of fludarabine, cyclophosphamide, and rituximab vs. pentostatin, cyclophosphamide, and rituximab in B-cell chronic lymphocytic leukemia.Invest New Drugs. 2012 Jun;30(3):1232-40. Epub 2011 Sep 16.
Nabhan, et Al. Purine nucleoside analogues and combination therapies in B-cell chronic lymphocytic leukemia: dawn of a new era. Leukemia Res. 28 429.
Wang J, Liu Y, Liu Y, et al. Time-resolved protein activation by proximal decaging in living systems[J]. Nature. 2019 May;569(7757):509-513.
Wang J, Liu Y, Liu Y, et al. Time-resolved protein activation by proximal decaging in living systems. Nature. 2019, 569(7757): 509-513.
Klohs Klohs WD., et al. Pentostatin: future directions. Pharmacol.Rev. 44 459.
Grever MR.Hairy cell leukemia: a successful model for experimental therapeutics--pentostatin and new ideas.Leuk Lymphoma. 2011 Jun;52 Suppl 2:25-8.