NCB-0846

TargetMol
Product Code: TAR-T4011
Supplier: TargetMol
CodeSizePrice
TAR-T4011-1mg1mg£95.00
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TAR-T4011-5mg5mg£128.00
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Quantity:
TAR-T4011-1mL1 mL * 10 mM (in DMSO)£134.00
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Quantity:
TAR-T4011-10mg10mg£168.00
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TAR-T4011-25mg25mg£282.00
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TAR-T4011-50mg50mg£430.00
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Quantity:
TAR-T4011-100mg100mg£600.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
NCB-0846 is an orally active TNIK inhibitor (IC50: 21 nM).
CAS:
1792999-26-8
Formula:
C21H21N5O2
Molecular Weight:
375.432
Pathway:
Cytoskeletal Signaling; MAPK; Stem Cells
Purity:
0.9897
SMILES:
O[C@H]1CC[C@H](CC1)Oc1cccc2cnc(Nc3ccc4nc[nH]c4c3)nc12
Target:
MAPK; Wnt/beta-catenin

References

Masuda M, et al. TNIK inhibition abrogates colorectal cancer stemness. Nat Commun. 2016 Aug 26;7:12586.