OTS964 hydrochloride

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TargetMol
Product Code: TAR-T4135
Supplier: TargetMol
CodeSizePrice
TAR-T4135-1mg1mg£101.00
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TAR-T4135-2mg2mg£114.00
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TAR-T4135-5mg5mg£139.00
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TAR-T4135-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T4135-10mg10mg£172.00
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TAR-T4135-25mg25mg£237.00
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TAR-T4135-50mg50mg£367.00
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TAR-T4135-100mg100mg£511.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
OTS964 is a potent and selective TOPK inhibitor with potential anticancer activity.
CAS:
1338545-07-5
Formula:
C23H25ClN2O2S
Molecular Weight:
428.98
Pathway:
MAPK; Apoptosis; Cell Cycle/Checkpoint
Purity:
0.9802
SMILES:
Cl.C[C@@H](CN(C)C)c1ccc(cc1)-c1c(O)cc(C)c2[nH]c(=O)c3sccc3c12
Target:
Apoptosis; TOPK; CDK

References

Wang J, Luo L, Ding Q, et al. Development of a Multi-Target Strategy for the Treatment of Vitiligo via Machine Learning and Network Analysis Methods. Frontiers in pharmacology. 2021, 12. Matsuo Y, et al. TOPK inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis. Sci Transl Med. 2014 Oct 22;6(259):259ra145