AG-494
Code | Size | Price |
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TAR-T4205-5mg | 5mg | £115.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T4205-1mL | 1 mL * 10 mM (in DMSO) | £119.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T4205-10mg | 10mg | £144.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T4205-25mg | 25mg | £202.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T4205-50mg | 50mg | £276.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T4205-100mg | 100mg | £401.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
AG-494 is an inhibitor of epidermal growth factor receptor kinase.
CAS:
133550-35-3
Formula:
C16H12N2O3
Molecular Weight:
280.283
Pathway:
Cell Cycle/Checkpoint; Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Purity:
0.995
SMILES:
Oc1ccc(C=C(/C#N)C(=O)Nc2ccccc2)cc1O
Target:
EGFR; CDK
References
Sagara, Y. et al. Tyrphostins protect neuronal cells from oxidative stress. The Journal of Biological Chemisty 277(39), 36204-36215 (2002).
Gazit, A. et al. Tyrphostins I: Synthesis and biological activity of protein tyrosine kinase inhibitors. Journal of Medicinal Chemistry 32(10), 2344-2352 (1989).