Belizatinib

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TargetMol
Product Code: TAR-T4257
Supplier: TargetMol
CodeSizePrice
TAR-T4257-1mg1mg£99.00
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TAR-T4257-2mg2mg£112.00
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TAR-T4257-5mg5mg£142.00
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TAR-T4257-1mL1 mL * 10 mM (in DMSO)£161.00
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TAR-T4257-10mg10mg£185.00
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TAR-T4257-25mg25mg£302.00
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TAR-T4257-50mg50mg£389.00
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TAR-T4257-100mg100mg£517.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Belizatinib is an effective, oral and dual inhibitor of ALK (IC50: 0.7 nM, wild-type recombinant ALK) and TRKA, TRKB, and TRKC.
CAS:
1357920-84-3
Formula:
C33H44FN5O3
Molecular Weight:
577.75
Pathway:
Angiogenesis; Tyrosine Kinase/Adaptors
Purity:
0.9948
SMILES:
CC(C)NC(=O)[C@H]1CC[C@H](CC1)n1c(NC(=O)c2ccc(F)cc2)nc2ccc(CN3CCC(CC3)C(C)(C)O)cc12
Target:
Trk receptor; ALK

References

Sullivan I, et al. ALK inhibitors in non-small cell lung cancer: the latest evidence and developments. Ther Adv Med Oncol. 2016 Jan;8(1):32-47