SRI-011381

TargetMol
Product Code: TAR-T4283
Supplier: TargetMol
CodeSizePrice
TAR-T4283-1mg1mg£95.00
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TAR-T4283-2mg2mg£103.00
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TAR-T4283-1mL1 mL * 10 mM (in DMSO)£107.00
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TAR-T4283-5mg5mg£122.00
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TAR-T4283-10mg10mg£161.00
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TAR-T4283-25mg25mg£262.00
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TAR-T4283-50mg50mg£389.00
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TAR-T4283-100mg100mg£597.00
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TAR-T4283-200mg200mg£808.00
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TAR-T4283-500mg500mg£1,163.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
CAS:
1629138-41-5
Formula:
C20H31N3O
Molecular Weight:
329.488
Pathway:
Stem Cells
Purity:
0.9911
SMILES:
O=C(NC1CCCCC1)N(CC1CCNCC1)Cc1ccccc1
Target:
TGF-beta/Smad

References

Qian Wu, et al. Astrocytic YAP protects the optic nerve and retina in an experimental autoimmune encephalomyelitis model through TGF-? signaling. Theranostics. 2021 Jul 25;11(17):8480-8499. Jingyin Han, et al. The Improvement Effect of Sodium Ferulate on the Formation of Pulmonary Fibrosis in Silicosis Mice Through the Neutrophil Alkaline Phosphatase 3 (NALP3)/Transforming Growth Factor-?1 (TGF-?1)/?-Smooth Muscle Actin (?-SMA) Pathway.