PHTPP

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TargetMol
Product Code: TAR-T4388
Supplier: TargetMol
CodeSizePrice
TAR-T4388-2mg2mg£101.00
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TAR-T4388-5mg5mg£119.00
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TAR-T4388-1mL1 mL * 10 mM (in DMSO)£124.00
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TAR-T4388-10mg10mg£145.00
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TAR-T4388-25mg25mg£217.00
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TAR-T4388-50mg50mg£328.00
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TAR-T4388-100mg100mg£516.00
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TAR-T4388-500mg500mg£1,050.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
PHTPP is a selective ERβ antagonist.
CAS:
805239-56-9
Formula:
C20H11F6N3O
Molecular Weight:
423.318
Pathway:
Endocrinology/Hormones
Purity:
0.9972
SMILES:
Oc1ccc(cc1)-c1c(nn2c(cc(nc12)C(F)(F)F)C(F)(F)F)-c1ccccc1
Target:
Estrogen Receptor/ERR; Estrogen/progestogen Receptor

References

Wang K, Chen Y, Gao S, et al. Norlichexanthone purified from plant endophyte prevents postmenopausal osteoporosis by targeting ER? to inhibit RANKL signaling[J].. Acta Pharmaceutica Sinica B. 2021, 11(2): 442-455 Wang K, Chen Y, Gao S, et al Norlichexanthone purified from plant endophyte prevents postmenopausal osteoporosis by targeting ER? to inhibit RANKL signaling. Acta Pharmaceutica Sinica B. 2020 Wang K, Chen Y, Gao S, et al. Norlichexanthone purified from plant endophyte prevents postmenopausal osteoporosis by targeting ER? to inhibit RANKL signaling[J]. Acta Pharmaceutica Sinica B. 2020 Compton DR, etal. Pyrazolo[1,5-a]pyrimidines: estrogen receptor ligands possessing estrogen receptor beta antagonist activity. J Med Chem. 2004 Nov 18;47(24):5872-93. Cui S, Suo N, Yang Y, et al.The aminosteroid U73122 promotes oligodendrocytes generation and myelin formation.Acta Pharmacologica Sinica.2023: 1-12.