SR17018

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TargetMol
Product Code: TAR-T4407
Supplier: TargetMol
CodeSizePrice
TAR-T4407-5mg5mg£122.00
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Quantity:
TAR-T4407-1mL1 mL * 10 mM (in DMSO)£127.00
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Quantity:
TAR-T4407-10mg10mg£148.00
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Quantity:
TAR-T4407-25mg25mg£242.00
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Quantity:
TAR-T4407-50mg50mg£349.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T4407-100mg100mg£523.00
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Quantity:
TAR-T4407-200mg200mg£702.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM.
CAS:
2134602-45-0
Formula:
C19H18Cl3N3O
Molecular Weight:
410.72
Pathway:
Neuroscience; Endocrinology/Hormones; GPCR/G Protein
Purity:
0.9973
SMILES:
Clc1ccc(CN2CCC(CC2)n2c3cc(Cl)c(Cl)cc3[nH]c2=O)cc1
Target:
Opioid Receptor

References

Zhuang Y, Wang Y, He B, et al. Molecular recognition of morphine and fentanyl by the human ?-opioid receptor. Cell. 2022, 185(23): 4361-4375. e19. Schmid CL,etal.Bias Factor and Therapeutic Window Correlate to Predict Safer Opioid Analgesics.Cell. 2017 Nov 16;171(5):1165-1175.