ZT-12-037-01

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TargetMol
Product Code: TAR-T5597
Supplier: TargetMol
CodeSizePrice
TAR-T5597-1mg1mg£95.00
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TAR-T5597-2mg2mg£106.00
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TAR-T5597-5mg5mg£125.00
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TAR-T5597-1mL1 mL * 10 mM (in DMSO)£131.00
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TAR-T5597-10mg10mg£164.00
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TAR-T5597-25mg25mg£260.00
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TAR-T5597-50mg50mg£438.00
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TAR-T5597-100mg100mg£611.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Zt-12-037-01 is a ATP competitive STK19 inhibitor?IC50 values of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N),respectively).
CAS:
2328073-61-4
Formula:
C21H31N5O2
Molecular Weight:
385.512
Pathway:
MAPK; Proteases/Proteasome; GPCR/G Protein
Purity:
0.98
SMILES:
COc1cc2nc(NC3CC3)nc(NC3CCN(CC3)C(C)C)c2cc1OC
Target:
Serine Protease; Ras

References

Yin C, Zhu B, Zhang T, et al.Pharmacological Targeting of STK19 Inhibits Oncogenic NRAS-Driven Melanomagenesis[J].Cell. 2019 Feb 21;176(5):1113-1127.