Pacritinib

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TargetMol
Product Code: TAR-T6020
Supplier: TargetMol
CodeSizePrice
TAR-T6020-2mg2mg£98.00
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TAR-T6020-5mg5mg£115.00
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TAR-T6020-1mL1 mL * 10 mM (in DMSO)£119.00
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TAR-T6020-10mg10mg£142.00
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TAR-T6020-25mg25mg£193.00
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TAR-T6020-50mg50mg£262.00
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TAR-T6020-100mg100mg£389.00
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TAR-T6020-500mg500mg£817.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Pacritinib (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).
CAS:
937272-79-2
Formula:
C28H32N4O3
Molecular Weight:
472.589
Pathway:
Stem Cells; JAK/STAT signaling; Angiogenesis; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
Purity:
0.9952
SMILES:
C(CN1CCCC1)Oc1ccc2Nc3nccc(n3)-c3cccc(COCC=CCOCc1c2)c3
Target:
FLT; Tyrosine Kinases; JAK

References

Hart S, et al. Blood Cancer J, 2011, 1(11), e44. Hart S, et al. Leukemia, 2011, 25(11), 1751-1759. Chen K Y, Krischuns T, Varga L O, et al. A highly sensitive cell-based luciferase assay for high-throughput automated screening of SARS-CoV-2 nsp5/3CLpro inhibitors. Antiviral Research. 2021