Tepotinib

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TargetMol
Product Code: TAR-T6121
Supplier: TargetMol
CodeSizePrice
TAR-T6121-1mg1mg£105.00
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TAR-T6121-2mg2mg£119.00
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TAR-T6121-5mg5mg£161.00
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TAR-T6121-1mL1 mL * 10 mM (in DMSO)£168.00
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TAR-T6121-10mg10mg£236.00
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TAR-T6121-25mg25mg£426.00
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TAR-T6121-50mg50mg£532.00
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TAR-T6121-100mg100mg£619.00
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TAR-T6121-500mg500mg£1,235.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Tepotinib is an inhibitor of MET tyrosine kinase with potential antineoplastic activity.
CAS:
1100598-32-0
Formula:
C29H28N6O2
Molecular Weight:
492.583
Pathway:
Tyrosine Kinase/Adaptors
Purity:
0.9981
SMILES:
CN1CCC(COc2cnc(nc2)-c2cccc(Cn3nc(ccc3=O)-c3cccc(c3)C#N)c2)CC1
Target:
Trk receptor; c-Met/HGFR; TAM Receptor

References

Bladt F, et al. Clin Cancer Res, 2013, 19(11), 2941-2951. Li P, Jia C, Fan Z, et al.Discovery of novel exceptionally potent and orally active c-MET PROTACs for the treatment of tumors with MET alterations.Acta Pharmaceutica Sinica B.2023