KRN-633

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TargetMol
Product Code: TAR-T6137
Supplier: TargetMol
CodeSizePrice
TAR-T6137-1mg1mg£103.00
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TAR-T6137-2mg2mg£118.00
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TAR-T6137-5mg5mg£148.00
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TAR-T6137-1mL1 mL * 10 mM (in DMSO)£156.00
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TAR-T6137-10mg10mg£193.00
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TAR-T6137-25mg25mg£274.00
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TAR-T6137-50mg50mg£367.00
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TAR-T6137-100mg100mg£511.00
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TAR-T6137-500mg500mg£1,026.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
KRN-633 is an effective VEGFR inhibitor. The IC50s of KRN-633 for VEGFR1, VEGFR2, and VEGFR3 is 170, 160 and 125 nM, respectively.
CAS:
286370-15-8
Formula:
C20H21ClN4O4
Molecular Weight:
416.86
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis
Purity:
0.9965
SMILES:
CCCNC(=O)Nc1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1Cl
Target:
VEGFR

References

Ban HS, et al. Cancer Lett, 2010, 296(1), 17-26. Nakamura K, et al. Mol Cancer Ther, 2004, 3(12), 1639-1649. Wada Y, et al. J Pharmacol Sci, 2010, 112(3), 290-298.