SU9516

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TargetMol
Product Code: TAR-T6167
Supplier: TargetMol
CodeSizePrice
TAR-T6167-1mg1mg£95.00
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TAR-T6167-2mg2mg£105.00
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TAR-T6167-5mg5mg£124.00
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TAR-T6167-1mL1 mL * 10 mM (in DMSO)£125.00
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TAR-T6167-10mg10mg£155.00
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TAR-T6167-25mg25mg£246.00
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TAR-T6167-50mg50mg£389.00
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TAR-T6167-100mg100mg£544.00
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TAR-T6167-500mg500mg£1,099.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
SU9516 is a potent CDK2 inhibitor, with an IC50 of 22 nM, and also has inhibitory effects on CDK1 and CDK4, with IC50s of 40 nM and 200 nM, respectively.
CAS:
377090-84-1
Formula:
C13H11N3O2
Molecular Weight:
241.25
Pathway:
MAPK; Cell Cycle/Checkpoint; Cytoskeletal Signaling; Autophagy; Chromatin/Epigenetic; Apoptosis
Purity:
0.9995
SMILES:
COc1ccc2NC(=O)C(=C/c3cnc[nH]3)c2c1
Target:
Apoptosis; p38 MAPK; CDK; PKC; Autophagy

References

Uchiyama H, et al. Cancer Sci. 2010, 101(3), 728-734. Leontovich AA, et al. Oncol Rep. 2013, 29(5), 1785-1788. Gao N, et al. Mol Pharmacol. 2006, 70(2), 645-655. Lane ME, et al. Cancer Res. 2001, 61(16), 6170-6177.