ISRIB (trans-isomer)

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TargetMol
Product Code: TAR-T6183
Supplier: TargetMol
CodeSizePrice
TAR-T6183-2mg2mg£103.00
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TAR-T6183-5mg5mg£124.00
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TAR-T6183-10mg10mg£151.00
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TAR-T6183-25mg25mg£228.00
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TAR-T6183-50mg50mg£346.00
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TAR-T6183-100mg100mg£567.00
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TAR-T6183-500mg500mg£1,139.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
ISRIB (trans-isomer), the trans-isomer of ISRIB, is a effective and specific PERK inhibitor (IC50: 5 nM).
CAS:
1597403-47-8
Formula:
C22H24Cl2N2O4
Molecular Weight:
451.34
Pathway:
Autophagy; Apoptosis
Purity:
0.9927
SMILES:
Clc1ccc(OCC(=O)N[C@H]2CC[C@@H](CC2)NC(=O)COc2ccc(Cl)cc2)cc1
Target:
Apoptosis; PERK; Autophagy

References

Sidrauski C, et al. Elife. 2013, 2, e00498.